Disease Monograph… Febrile Non-Haemolytic Transfusion Reaction 8 Jun 2018 Febrile non-haemolytic transfusion reaction (FNHTR) is the most common transfusion reaction. Its needs to be differentiated from haemolytic transfusion reaction and bacterial contamination both of which are serious and potentially…
Disease Monograph… Nodular Lymphocytic Predominant Hodgkin’s Lymphoma 20 Oct 201720 Oct 2017 Hodgkin lymphoma (HL) is of two types. Classical (cHL) and nodular lymphocyte predominant (NLPHL). NLPHL is rarer and runs a more indolent clinical course. Epidemiology NLPHL accounts for about 5%…
Disease Monograph… Drugs and Eosinophilia 25 Jan 20173 Feb 2017 Drugs, prescription and non-prescription, and nutritional supplements are a common cause of eosinophilia across the world. In regions with a low prevalence of parasitic infestations drugs are the leading cause…
Anemia… Sickle β-Thalassaemia 24 Sep 201624 Sep 2016 Sickle cell anaemia and β-thalassaemia are two common haemoglobinopathies. Co-inheritance of the two is called sickle β-thalassaemia. Sickle β-thalassaemia seen in Africa, throughout the Mediterranean, Arabian Peninsula and sporadically in india.…
Diffuse Large B Cell Lymphoma… Primary Cutaneous DLBCL – Leg Type 1 Jan 2015 The first description of a primary cutaneous diffuse large B cell lymphoma was by Willemze et al in 1987 who described a group of elderly women with cutaneous large cell…
Acute Lymphoblastic Leukaemia… Hyperleukocytosis and Leukostasis 10 Jul 20146 Sep 2017 Leukostasis is a oncological emergency seen in patients with leukaemia who present with pronounced leucocytosis. It is seen in about 5-30% of adult acute leukaemia cases. It results from slugging of microcirculation…
Disease Monograph… Overwhelming Post-Splenectomy Infection (OPSI) 25 Feb 20144 Nov 2015 Splenectomy is a treatment for haematological disorders, palliation of hypersplenism, symptom relief in patients with symptomatic splenomegaly, splenic trauma and as a diagnostic procedure when tha pathology can not be…
Acute Lymphoblastic Leukaemia… Osteonecrosis in Acute Lymphoblastic Leukaemia (ALL) 10 Nov 2013 Corticosteroids are an important component of treatment of childhood ALL. The use of corticosteroids ahs been associated with osteonecrosis. The estimates of osteonecrosis have varied from 7.4%-44%. About 25% of…
Disease Monograph… Primary Testicular Lymphoma 29 Aug 201216 Oct 2015 Primary testicular lymphoma constitutes 1-2% of non-Hodgkin’s lymphomas and 5% or lesser of testicular tumours. It has a poorer prognosis than other NHLs. The survival curves do not plateau indication…
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