Classical Hodgkin Lymphoma… From Hodgkin’s Disease to Hodgkin Lymphoma 21 Oct 201521 Oct 2015 Hodgkin lymphoma was described by Thomas Hodgkin in 1932. It was referred to as Hodgkin's disease till the WHO classification proposed the use of the term Hodgkin Lymphoma. The journey…
Acute Lymphoblastic Leukaemia… Leukaemia – The Peripheral Smear 10 Jul 2014 Differentiating Acute and Chronic Leukaemia Leucocytosis with anaemia is a feature of acute and chronic leukaemia. It is possible to differentiate acute and chronic leukaemia by looking at the peripheral…
Haematology Atlas… Monocyte and Neutrophils 6 Dec 2013 The photomicrograph above shows a monocyte (left) and two neutrophils(right) and highlights the differences between the two. The monocyte is mononuclear cell 12-20µm in diameter (about 1.5-2.5 times an erythrocyte).…
Bone Marrow Examination… Multiple Myeloma – Plasma Cells 17 Sep 20131 Feb 2018 Normal plasma cells are 15-20 μm in diameter, have an eccentric nucleus and a pale blue cytoplasm. there is a perinuclear halo which corresponds to the Golgi apparatus. The cytoplasm…
Clonal Plasma Cell Disorder… Biclonal Gammopathy 13 Sep 2013 A 53 year old patient presented with backache. A skeletal survey was performed that showed punched out lesions in the skull. The bone marrow aspiration showed 21% plasma cells. The…
Cytoplasmic Inclusions… Toxic Granules in Neutrophils 23 Mar 2013 Granulocytes have two types of granules primary and secondary. Primary granules are azurophilic, most numerous and prominent at the promyelocyte stage (see morphology of myeloid precursors) and diminish in number…
Haematology Atlas… Photomicrography with a Canon 7D SLR 19 Mar 201319 Mar 2013 "Necessity is the mother of invention (or actually discovery in this case)" This blog is developed from a manuscript of a haematology book. No haematology book can be complete without…
Diagnosis… Myelocyte and Neutrophils – Band and Segmented 18 Mar 201318 Mar 2013 The image about shows morphology of cells of the neutrophilic series. The first cell to show commitment to a particular granulcoytic series (eosinophilic, basophilic or eosinophilic) is the promyelocyte. The…
Diagnosis… Lymphocytes 11 Mar 201313 Mar 2013 There are two types of lymphocytes small (10-12µm) and large (12-16µm). Most of the lymphocytes in the peripheral blood are small. The nucleus of he lymphocytes is small, round, usually…
Haematology Atlas… Monocyte 11 Mar 201311 Mar 2013 Monocytes are the largest leucocytes. They vary considerable in size and shape and may measure about 12-20 µm in diameter. The have a lobulated nucleus that is centrally placed with…
All About Blood 