Follicular Lymphoma… Follicular Lymphoma – Epidemiology 3 Aug 201816 Mar 2019 Follicular lymphoma (FL) is one of the most common types of non-hodgkin lymphoma. Its incidence is second to only diffuse large B cell lymphoma. It is slightly more common in…
Lymphoma… Marginal Zone Lymphoma 25 Apr 201825 Apr 2018 Marginal zone lymphomas are low grade lymphoma that are believed to arise from the lymphocytes of the marginal zone of lymphoid follicles. The marginal zone lies outside the mantle zone.…
Disease Monograph… Nodular Lymphocytic Predominant Hodgkin’s Lymphoma 20 Oct 201720 Oct 2017 Hodgkin lymphoma (HL) is of two types. Classical (cHL) and nodular lymphocyte predominant (NLPHL). NLPHL is rarer and runs a more indolent clinical course. Epidemiology NLPHL accounts for about 5%…
Acute Lymphoblastic Leukaemia… Evaluation of Splenomegaly 17 May 201717 May 2017 The spleen is a secondary lymphoid organ that lies in intraperitoneally in the left hypochondrium, abuting the diaphragm. It spans from the 9th to 11th rib and weighs between 150-200g. Spleen…
Lymphoma… The M-Band 29 Jun 201610 Jun 2018 What is an M-Band? Immunoglobulins are antigen binding molecules secreted by plasma cells. Immunoglobulins bind antigens and play a role acquired immunity. Plasma cells develop from antigen exposed B-lymphocytes. The…
Burkitt's Lymphoma… Classification of Lymphoma 3 May 20161 Feb 2018 Lymphomas are a group of malignancies arising from lymphoid tissue. They have a diverse etiology, pathogenesis, clinical presentation, treatment and outcomes. Morphology alone is insufficient to classify lymphomas but for a long…
Classical Hodgkin Lymphoma… From Hodgkin’s Disease to Hodgkin Lymphoma 21 Oct 201521 Oct 2015 Hodgkin lymphoma was described by Thomas Hodgkin in 1932. It was referred to as Hodgkin's disease till the WHO classification proposed the use of the term Hodgkin Lymphoma. The journey…
Diffuse Large B Cell Lymphoma… Primary Cutaneous DLBCL – Leg Type 1 Jan 2015 The first description of a primary cutaneous diffuse large B cell lymphoma was by Willemze et al in 1987 who described a group of elderly women with cutaneous large cell…
Clinical Evaluation… Manifestations of Lymphoma 30 Dec 201424 May 2016 Lymphomas are the most prevalent haematological malignancies. They are highly curable particularly in the early stage. As is the case with all cancers, there are no symptoms typical of lymphoma.…
Acute Lymphoblastic Leukaemia… Tumour Lysis Syndrome 9 Oct 20149 Oct 2014 Rapid tumour lysis can release harmful metabolites at a rate that exceeds the kidney's excretory capacity resulting in a metabolic syndrome known as tumour lysis syndrome (TLS). TLS is a complex…
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