Haemachromatosis… Transferrin and Transferrin Receptors 27 Sep 2014 Free iron is toxic by its ability to generate oxygen free radicals and cause damage to macromolecules. Iron in transported in the plasma bound to transferrin. Uptake of transferrin by the…
Anemia… Intestinal Iron Absorption 18 Jan 201429 Apr 2017 Intestinal absorption of iron (figure 1) Iron absorption occurs in two steps Absorption of iron into the enterocyte at the luminal surface of the enterocytes Transport of iron to the…
Anemia… Hepcidin and Ferroportin 18 Jan 2014 Iron is an essential micronutrient that is toxic because of its ability to form oxygen free radicals that can damage macromolecules. It is this property of iron that makes it…
Anemia… Distribution of Body Iron 16 Jan 201416 Jan 2014 Body Iron Stores Iron is normally stored in the reticuloendothelial system and the hepatocyte. The total body iron varies with age and gender. Iron Stores at birth The total body…