Bone Marrow Examination… Multiple Myeloma – Plasma Cells 17 Sep 20131 Feb 2018 Normal plasma cells are 15-20 μm in diameter, have an eccentric nucleus and a pale blue cytoplasm. there is a perinuclear halo which corresponds to the Golgi apparatus. The cytoplasm…
Diagnosis… Myelocyte and Neutrophils – Band and Segmented 18 Mar 201318 Mar 2013 The image about shows morphology of cells of the neutrophilic series. The first cell to show commitment to a particular granulcoytic series (eosinophilic, basophilic or eosinophilic) is the promyelocyte. The…
Bone Marrow Examination… Normoblast Maturation 7 Mar 20138 Mar 2013 The image above shows three polychromatophilic normoblasts. The one on the left is the least mature and the one on the right the most mature. Maturation is associated with Decrease…
Bone Marrow Examination… Orthochromatophilic Normoblast 7 Mar 20137 Mar 2013 Orthochromatophilic normoblast An orthochromatophilic normoblast is the most mature of nut;elated red cell precursors. The cytoplasm has lost almost all it's basophilia and is the same colour as that of…
Bone Marrow Examination… Megaloblasts 25 Jul 20123 Jan 2015 Development of erythrocytes involves coordinated changes in the nucleus and the cytoplasm of erythroid processors (see Morphology of Erythroid Precursors) . The proerythroblast is a large cell with a fine…
Bone Marrow Examination… Osteoclast Morphology 18 Jun 201219 Jun 2012 This was a 32 year old patient whose bone marrow aspiration was done for a suspected diagnosis of a leukaemia. The aspirate yielded a scanty amount of pauciparticulate marrow. Blasts…
Anemia Bone Marrow Involvement by Cancer 16 Jun 2012 A 48 year old women presented with backache. The MRI suggested the presence of a metastatic involvement of multiple vertebrae. The biopsy from D11 showed it to involved by an…
Acute Promyelocytic Leukemia… Faggot Cells 30 May 201213 Jun 2012 The old/middle english term faggot means a bundle of sticks bound together as fuel (faggot is derived the latin term fascis which is also the root for the term fasiculus).…
Erythropoiesis… Basophilic and Polychromatophilic Normoblasts 22 May 201213 Jun 2012 The adjacent image shows three erythroid cells, two polychromatophilic normoblasts on the sides and a basophilic normoblasts between the two cells. The color of cytoplasm of erythroid cells is balance…
Acute Myeloid Leukemia… Cluster of Differentiation 20 Mar 201220 Mar 2012 Table 1 Cluster of differentiation was proposed as a system to classify monoclonal antibodies. The antibodies, their cluster of differentiation and their linage is listed in the table above The…
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