Anemia… Clinical Manifestation of Iron Deficiency 25 Feb 201425 Feb 2014 The manifestations of Iron deficiency evolve insidiously and are multi-systemic. They include Anaemia Iron deficiency causes hypochromic microcytic anaemia. The anaemia has an insidious onset and the patient may become…
Anemia… The Erythrocyte Membrane 4 Feb 201411 Oct 2017 Compared to other cells of the body the erythrocyte, consistent with its simple functional requirements, has a simple structure. The erythrocyte delivers oxygen to tissue and aids in carriage of…
Anemia… Erythrocyte Metabolism 6 Aug 20137 Aug 2013 As erythrocytes lack mitochondria they are not able to use fats or generate energy from Krebs cycle. Though they have enzymes to synthesize glycogen the balance between synthesis and breakdown…
Anemia… Case No 1 – Severe Microcytic Anaemia 1 Nov 20125 Nov 2012 A 17-year-old woman from a farming community presented with the history of severe weakness, fatigue and dyspnoea on moderate exertion. She was well till about 4 months before presentation when…
Haematopathology… Red Cell Indices 13 Oct 201217 Oct 2012 Estimation of haemoglobin concentration, erythrocyte count, haematocrit, total and differential leucocyte count and platelet count along with examination of the peripheral smear are a part of evaluation of anaemia. Examination…
Anemia… Red Cell Distribution Width 1 Oct 2012 Features of peripheral smear like erythrocyte size, haemoglobinization and variability in size have long been useful in evaluation of patients with anaemia. The definitions of these parameters before the advent of…
Anemia… Evaluating Anaemia 28 Sep 201228 May 2016 Anaemia is not disease but a manifestation of an underlying disease. The list of diseases causing anaemia is exhaustive. The list includes disease as innocuous as a nutritional iron deficiency…
Anemia… Pathophysiology of Anaemia 3 Jul 20129 Jul 2012 Low haemoglobin decreases the oxygen carrying capacity of the blood. This is offset by the following mechanisms. Increased cardiac output: Tissue hypoxia causes peripheral vasodialatation and decreased haemoglobin decreases blood…
Haematology Atlas… Clinical Manifestations of Polycythaemia 19 Jun 2012 Figure 1. Plethora of the face Figure 2. Plathoric mucosa Figure 3. Palmar erythrma This 50 year old male presented with an incidentally diagnosed haemoglobin of 21.2g/dL. He had no…
Haematology Atlas… Normal Erythrocytes 26 May 201213 Jun 2012 Normal erythrocytes are round disks about 7.5μm in diameter.The central one third is paler than the periphery because of the discoid shape of the erythrocyte. The picture above is a 40X…
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