Erythropoiesis… Regulation of Haematopoiesis 23 Mar 2019 All blood cells arise from the haemaopoietic stem cell. The path along which the stem cell progeny matures is dictated by the needs of the body. Examples of this include…
Anaemia of Renal Insufficiency… Anaemia of Renal Insufficiency 24 Aug 201724 Aug 2017 Richard Bright discovered the relationship of renal failure and anaemia in 1836. Anaemia of renal insufficiency is mainly results from decreased erythropoietin production and impaired supply of iron to erythroid…
Anemia… Oral Iron Therapy 1 May 20171 May 2017 Iron deficiency anaemia is treated by iron supplementation that may be administered orally or parenterally. Oral iron absorption is inefficient, is interfered by food and is associated with high incidence…
Erythropoiesis… Etiology of Polycythaemia 13 Jul 201313 Jul 2013 The terms polycythemia and erythrocytosis though used interchangeably describe different entities. Polycythemia (Gk, polys + kytos, cell, haima, blood) is an absolute increase in the mass of red cells. Erythrocytosis refers to only increase in the concentration…
Erythropoiesis… Erythropoietin and Erythropoietin Receptor 23 Dec 201122 Jun 2017 (Post updated on June 21st 2017) Erythropoietin (EPO), a 34kD 166 amino acid polypeptide, is the main regulator of erythrocyte production. It acts via the erythropoietin receptor (EPOR). Importance of…