Bone Marrow Examination… Osteoclast Morphology 18 Jun 201219 Jun 2012 This was a 32 year old patient whose bone marrow aspiration was done for a suspected diagnosis of a leukaemia. The aspirate yielded a scanty amount of pauciparticulate marrow. Blasts…
Anemia Bone Marrow Involvement by Cancer 16 Jun 2012 A 48 year old women presented with backache. The MRI suggested the presence of a metastatic involvement of multiple vertebrae. The biopsy from D11 showed it to involved by an…
Acute Promyelocytic Leukemia… Faggot Cells 30 May 201213 Jun 2012 The old/middle english term faggot means a bundle of sticks bound together as fuel (faggot is derived the latin term fascis which is also the root for the term fasiculus).…
Haematology Atlas… Normal Erythrocytes 26 May 201213 Jun 2012 Normal erythrocytes are round disks about 7.5μm in diameter.The central one third is paler than the periphery because of the discoid shape of the erythrocyte. The picture above is a 40X…
Erythropoiesis… Basophilic and Polychromatophilic Normoblasts 22 May 201213 Jun 2012 The adjacent image shows three erythroid cells, two polychromatophilic normoblasts on the sides and a basophilic normoblasts between the two cells. The color of cytoplasm of erythroid cells is balance…
Haematology Atlas… Neutrophil and Lymphocyte 20 May 201213 Jun 2012 The image above shows a lymphocyte (left) and a polymprphonuclear neutrophil (right) in the peripheral blood. The lymphocyte is a cell about 10μ in size with a dense purple nucleus…
Leukaemia… Gingival Hypertrophy in Leukaemia 15 May 201213 Jun 2012 A 21 year old male presented with fever, weakness and petechiae. The haemogram showed a haemoglobin of 7.2g/dL, WBC count of 21.3 × 109/L and platelets of 23 × 109/L. Peripheral smear…
Anemia… Sickle Haemoglobin and Varients 14 May 201213 Jun 2012 Substitution of the amino acid glutamic acid by valine at position 6 of the beta globin gene (HBB glu6val) results in a mutant haemoglobin that polymerizes at low oxygen pressure. This…
Iron Deficiency Plummer-Vinson Syndrome/Paterson Kelly Syndrome 6 May 2012 In 1912 Plummer described dysphagia and spasm of the upper oesophagus without anatomical stenosis in patients with longstanding iron deficiency. In 1919, Vinson, Paterson and Kelly independently described patients with…
Bone Marrow Examination… Megakaryocyte Morphology 22 Dec 201123 Aug 2013 Megakaryocytes, the precursors of platelets, are the largest cells in the bone marrow. They are the earliest morphologically recognizable cells of the megakaryocyte-platelet lineage. Megakaryocytes arise from the stem cell…
All About Blood 