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Tag: HbS

Anemia…

Sickle β-Thalassaemia

24 Sep 201624 Sep 2016
Sickle cell anaemia and β-thalassaemia are two common haemoglobinopathies. Co-inheritance of the two is called sickle β-thalassaemia. Sickle β-thalassaemia seen in Africa, throughout the  Mediterranean, Arabian Peninsula and sporadically in india.…
Anemia…

Evolution and Spread of HbS

20 Jun 201620 Jun 2016
The gene for β globin (OMIM  is present on chromosome 11 (11p15.4) along with other globin genes (ε, γ, γ and δ). This is known as the β-globin cluster .…
Anemia…

Sickle Haemoglobin and Varients

14 May 201213 Jun 2012
Substitution of the amino acid glutamic acid by valine at position 6 of the beta globin gene (HBB glu6val) results in a mutant haemoglobin that polymerizes at low oxygen pressure. This…

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