Lymphocytosis in Adults

28 Sep 201728 Sep 2017

Normal Peripheral Blood Lymphocytes Lymphocytes are small leucocytes with a round nucleus and a thin rim of cytoplasm. About 10% of the peripheral lymphocytes are large, have a more abundant…

Drugs and Eosinophilia

25 Jan 20173 Feb 2017

Drugs, prescription and non-prescription,  and nutritional supplements are a common cause of eosinophilia across the world. In regions with a low prevalence of parasitic infestations drugs are the leading cause…

Hydroxyurea – Drug Information

15 Jul 201415 Jul 2014

Hydroxyurea was synthesised in Germany in 1860 and was found inhibit granulocyte production. It was only a hundred years after this that its potential as an anticancer drug was realized.…

Leukaemia – The Peripheral Smear

10 Jul 2014

Differentiating Acute and Chronic Leukaemia Leucocytosis with anaemia is a feature of acute and chronic leukaemia. It is possible to differentiate acute and chronic leukaemia by looking at the peripheral…

Large Granular Lymphocyte

24 Jul 201213 Mar 2013

Typically lymphocytes are small (10-12μm) cells with a scanty agranular cytoplasm with a round slightly indented nucleus. About 10% of lymphocytes are larger (12-16μ), have a nucleus which has a…

Determinants of Blood Viscosity

19 Mar 201219 Mar 2012

Fluids flow on application of pressure. The flow may be laminar flow that is orderly in parallel layers or turbulent flow that is chaotic. During laminar flow the layer closest…

Neutrophil Segmentation and Projections

18 May 20118 Jul 2012

The neutrophil nucleus is segmented. The nucleus of the most immature neutrophil, band neutrophil lacks segmentation. It differs from a metamyelocyte in that the concave and convex surfaces of the…