MCQ – Haemoglobinopathy

7 May 2019

Which of the following is least likely to have splenomegaly persisting to adulthood? β+ thalassaemia intermedia Sickle cell anaemia Sickle cell trait Sickle β+ thalassaemia   Which of the following is…

Sickle Cells

24 Aug 201331 Aug 2013

Sickle Cells 40X Sickle Cells - 100X Sickle Cells - 100X The three photomicrographs above show sickle cells from a patients with sickle cell anemia. Sickle cell anaemia occurs because…

Sickle Haemoglobin and Varients

14 May 201213 Jun 2012

Substitution of the amino acid glutamic acid by valine at position 6 of the beta globin gene (HBB glu6val) results in a mutant haemoglobin that polymerizes at low oxygen pressure. This…

Determinants of Blood Viscosity

19 Mar 201219 Mar 2012

Fluids flow on application of pressure. The flow may be laminar flow that is orderly in parallel layers or turbulent flow that is chaotic. During laminar flow the layer closest…

Detoxifying Haemoglobin

22 Jun 201127 Jun 2011

It is difficult to imagine that a molecule as essential to life as haemoglobin (hb) would need a detoxification mechanism. Anyone who has treated a patient with severe intravascular haemolysis…