Evaluation… Manifestations of Disease – MCQ – 1 21 May 2019 Q1. Which of the following is associated with clubbing and anaemia Bacterial endocarditis Congenital heart disease Thalassaemia Minor Haemoglobin E disease Q2. Which of the following is not a cause…
Anemia… MCQ – Microcytic Anaemia 3 Apr 20193 Apr 2019 1. Which of the following diagnosis can be excluded by the presence of microcytosis Aplastic anaemia Iron deficiency Paroxysmal nocturnal haemoglobinuria Sideroblastic anaemia 2. Which of the following are true…
Erythropoiesis… Regulation of Haematopoiesis 23 Mar 2019 All blood cells arise from the haemaopoietic stem cell. The path along which the stem cell progeny matures is dictated by the needs of the body. Examples of this include…
Multiple Choice Questions Multiple Choice Questions -1 22 Mar 201922 Mar 2019 1. A 45 year old male patient presents with eosinophilia and fever. Which of the following diagnosis is unlikely. Hodgkin lymphoma Typhoid fever Chronic Myeloid leukaemia Polyarteritis nodosa 2. 62 year…
Disease Monograph… Febrile Non-Haemolytic Transfusion Reaction 8 Jun 2018 Febrile non-haemolytic transfusion reaction (FNHTR) is the most common transfusion reaction. Its needs to be differentiated from haemolytic transfusion reaction and bacterial contamination both of which are serious and potentially…
Coagulation Disorders… Factor VII 7 Jun 2018 Factor VII is a vitamin K dependent coagulation factor. It is a serine protease. Activation of factor VII is the first step in the coagulation cascade. Deficiency is rare and…
Anti-coagulants… Vitamin K 6 Jun 20186 Jun 2018 Vitamin K was discovered by Henrik Dam in 1929 while studying cholesterol metabolism in chicken (see Discovery of Vitamin K and It's Targets and Antagonists). It is a co-factor for post translation…
Anemia… Treatment of Warm Antibody Type Autoimmune Haemolytic Anaemia (WAIHA) 20 Feb 201820 Feb 2018 Warm antibody type of autoimmune haemolytic anaemia (WAIHA) is characterised by anaemia, reticulocytosis, conjugated hyperbilirubinaemia with the presence of a positive anti-globulin (Coombs') test (see Diagnosis of haemolytic anaemia). It may…
Acquired Coagulation Defects… Clinical Features of Antiphospholipid Syndromes 8 Feb 20188 Feb 2018 Antiphospholipid syndrome (APS) is characterised by venous or arterial thrombosis and/or pregnancy morbidity in the presence of persistent laboratory evidence of antiphospholipid antibodies. It may occur as a primary disorder…
Disease Monograph… Nodular Lymphocytic Predominant Hodgkin’s Lymphoma 20 Oct 201720 Oct 2017 Hodgkin lymphoma (HL) is of two types. Classical (cHL) and nodular lymphocyte predominant (NLPHL). NLPHL is rarer and runs a more indolent clinical course. Epidemiology NLPHL accounts for about 5%…