Sickle Cells 40X |
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Sickle Cells – 100X |
Sickle Cells – 100X |
The three photomicrographs above show sickle cells from a patients with sickle cell anemia. Sickle cell anaemia occurs because an A→T substitution in codon 6 of the β globin chain of haemoglobin. The single nucleotide polymorphism results in valine substituting for glutamic acid resulting in the formation of haemoglobin S (HbS). HbS crystallizes in hypoxic conditions resulting in sickling of erythrocytes.
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Is there any cure for sickelcell anemia
The only cure for sickle cell anaemia is a allogenic stem cell transplant. This is a difficult procedure and has many side effects and is appropriate in very few sickie cell anaemia patients